John M. Belote . Professor Role of the ubiquitin/proteasome pathway in Drosophila developoment jbelote@syr.edu Office: 304 Biological Research Labs (BRL) Phone: 315-443-3695 / fax: 315-443-2012 Education: • Ph.D., University of North Carolina at Chapel Hill, 1979 • Postdoc, University of California-San Diego, 1979-1985 Courses: • BIO 326 Genetics and Cell Biology I • BIO 419 Jr/Sr Biology Honors Seminar • BIO 326 Genetics Laboratory • BIO 462/662 Molecular Genetics Interdisciplinary Programs: • Professor. SU Dept. of Chemistry, • Research Professor, SUNY Upstate Medical Univ., Dept. of Cell & Develop. Biology •Faculty member, SU SB3 Program

RESEARCH

Belote Lab at Syracuse University: http://biology.syr.edu/beloteresearch.html

Funding: National Science Foundation (MCB-04166467 Molecular genetic analysis of Drosophila proteasomes

SELECTED PUBLICATIONS:

Zhong, L. and J.M. Belote (2007) The testis-specific proteasome subunit Prosa6T of Drosophila melanogaster is required for individualization and nuclear maturation during spermatogenesis. Development 134: 3517-3525.

Maxwell, P.H., J.M. Belote and R.W. Levis (2006) Identification of multiple transcription initiation, polyadenylation, and splice sites in the Drosophila melanogaster TART family of telomeric retrotransposons. Nucleic Acids Res. 34: 5498-5507.

Neuburger, P. J., K. J. Saville, J. Zeng, K. A. Smyth and J.M. Belote (2006) A genetic suppressor of two dominant temperature sensitive (DTS) lethal proteasome mutants of Drosophila melanogaster is itself a mutated proteasome subunit gene. Genetics 173: 1377-1387.

Belote, J.M. and L. Zhong (2005) Proteasome gene duplications in mammals, flies and plants. Recent Research Developments in Genes & Genomes 1:107-129.

Ma, J., E. Katz, and J.M. Belote. (2002) Expression of proteasome subunit isoforms during spermatogenesis in Drosophila melanogaster. Insect Molec. Biol. 11: 624-639. [PDF]

Belote, J.M. and E. Fortier (2002) Targeted expression of dominant negative proteasome mutants in Drosophila. Genesis 34:80-82. [PDF]

Fortier, E. and J. M. Belote (2000) Temperature-dependent gene silencing by an expressed inverted repeat in Drosophila. Genesis 26:240-244. [PDF]

Smyth, K. A. and J. M. Belote (1999) The dominant temperature-sensitive lethal mutant DTS7 of Drosophila melanogaster encodes an altered 20S proteasome ß-type subunit. Genetics 151: 211-220. [PDF]