BRIAN R. CALVI. Associate Professor Cell cycle control of DNA replication and genome stability bcalvi at syr.edu Office: 703A Biological Research Labs (BRL) Phone: 315-443-1788 (office); 443-1843 (lab) / fax: 315-443-2012 Education: • Ph.D., Harvard University (Biology), 1993 • Postdoc, Carnegie Institution of Washington 1993-98 Courses: • Bio 327 Genetics and Cell Biology II • Bio 400/600 Modern Concepts in Biology • Bio 700 Cell cycle regulation in development and disease

RESEARCH

Calvi Lab at Syracuse University: http://biology.syr.edu/calviresearch.html

Funding:
• National Institutes of Health R01
• American Cancer Society Research Scholar award

SELECTED PUBLICATIONS:

B.R. Calvi Developmental Gene Amplification . In Eukaryotic DNA Replication and its relevance to Human Disease. Melvin DePamphilis (ed.) (2006).

May, N.R., Thomer, M., Murnen, K.F., and Calvi, B.R. (2005) Levels of the origin-binding protein Double parked and its inhibitor Geminin increase in response to replication stress. Journ. Cell Sci. 118, 4207-4217.

Bandura J.L., Beall E., Bell M, Silver H., Botchan, M., and Calvi, B.R. (2005) humpty dumpty is required for developmental DNA amplification and cell proliferation in Drosophila. Current Biology 15: 755-759.

Thomer, M., May, N.R., Aggarwal, B.D., Kwok, G., and Calvi, B.R. (2004). Drosophila double-parked is sufficient for re-replication during development and is regulated by Cyclin E / CDK2. Development 131(19): 4807-4818.

Aggarwal, B.D. and Calvi, B.R. (2004). Chromatin regulates origin activity in Drosophila follicle cells. Nature 430: 372-376.