r e s e a r c h.. p r o g r a m.. o v e r v i e w

Changes in cell shape and adhesion are two fundamental hallmarks of the differentiation of eucaryotic cells. To better understand the mechanistic basis of these processes we are studying their roles in the life cycle of the budding yeast, Saccharomyces cerevisiae. Three main projects are presently underway in the laboratory:

• Analyses of a novel paxillin homolog and Rho GTPase signaling modulator, Pxl1p
  
  
• Studies of the functions, traffic, and inhibition of fungal adhesins
  
  
• Functional genomics of fungal control of lipid and membrane homeostasis

Undergraduate students: Please click here for information about research opportunities in my lab.