Faculty and Research

Katharine (Kate) Lewis

Associate Professor

kelewi02@syr.edu
Office: LSC 262
Phone: 315-443-5902 Lab: 315-443-7253

Education

• BA (Honors), Cambridge University, 1990 - 1993
• Kennedy Memorial Scholar, Harvard University, 1993 - 1994
• Ph.D., University College London, 1994 - 1998
• Postdoc, University of Oregon, 1999 - 2003

Previous academic positions

• Royal Society University Research Fellow, University of Cambridge 2004-2010

Research interests

Specification and patterning of spinal cord interneurons; Formation of functional neuronal circuitry; Evolution of spinal cord patterning and function; Dorsal-ventral neural tube patterning; zebrafish development.

Lewis Research Link: http://biology.syr.edu/faculty/lewis/lewis_research.htm

Selected Publications

S. England, M. F. Batista, J. K. Mich, J. K. Chen and K. E. Lewis (2011) Roles of Hedgehog Pathway Components and Retinoic Acid Signalling in Specifying Zebrafish Ventral Spinal Cord Neurons. Development 138: 5121-5134.

D. K. Goode, H. A. Callaway, G. Cerda, K. E. Lewis and G. Elgar (2011) Minor change, major difference: divergent functions of highly conserved cis-regulatory elements subsequent to whole genome duplication events. Development 138: 879-884.

C. J. Schulte, C. Allen, S. England, J. Juárez-Morales and K. E. Lewis (2011) Evx1 is required for joint formation in zebrafish fin dermoskeleton. Developmental Dynamics 240: 1240-1248.

Cerda, G.A., Hargrave, M., and Lewis, K.E. (2009) RNA profiling of FAC-sorted neurons from the developing zebrafish spinal cord. Dev. Dyn. 238(1):150-161.

Wotton,K., Weierud F., Dietrich, S. and Lewis, K. E. (2008) Comparative genomics of Lbx loci reveals conservation of identical Lbx ohnologs in bony vertebrates. BMC Evolutionary Biology 8:171.

Batista, M.F., and Lewis, K.E. (2008) Pax2/8 act redundantly to specify glycinergic and GABAergic fates of multiple spinal interneurons. Dev. Biol. 323(1):88-97

Batista, M.F., Jacobstein, J., and Lewis, K.E. (2008) Zebrafish V2 cells develop into excitatory CiD and Notch signalling dependent inhibitory VeLD interneurons. Dev. Biol.. 322(2):263-275.

Lupo,G., Harris,W.A. and Lewis, K.E. (2006) Mechanisms of ventral patterning in the vertebrate nervous system. Nature Reviews Neuroscience. 7:103-114.

Lewis, K.E. (2006) How do genes regulate simple behaviours? Understanding how different neurons in the vertebrate spinal cord are genetically specified. Philos Trans R Soc Lond B Biol Sci.. 361(1465):45-66.

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