Eleanor Maine . Professor emmaine@syr.edu Office: 426 Lyman Hall Phone: 315-443-9169 / fax: 315-443-2012 Education: • Ph.D., Princeton University, 1984 • Postdoc, Princeton University, 1984-86 • Postdoc, University of Wisconsin-Madison, 1986-1990, Research Associate Courses: • BIO 421: Undergraduate Biology Seminar • BIO 462/662: Molecular Genetics • BIO 503: Developmental Biology • BIO 688: Biological Literature: Developmental Biology • BIO 785: Developmental Genetics/Signal Transduction Interdisciplinary Programs: • Faculty member, SU SB3 Program

RESEARCH

Genetic regulation of development; cell-signaling; germline development; RNA silencing

Maine Lab at Syracuse University: http://biology.syr.edu/maineresearch.html

Funding:
• National Science Foundation: Genetic and molecular analysis of meiotic silencing in C. elegans, 2006-2009

SELECTED PUBLICATIONS:

Maine, E.M. (2008) Studying gene function in Caenorhabditis elegans using RNA-mediated interference. Briefings in Functional Genomics and Proteomics, in press.

Liu,Y., and E.M. Maine (2007) The Bro1-domain protein, EGO-2, promotes Notch signaling in Caenorhabditis elegans.Genetics 177, 2265-2277. [PDF].

Maine, E.M., J. Hauth, T. Ratliff, V.E. Vought, X. She, and W.G. Kelly (2005). EGO-1, a putative RNA-dependent RNA polymerase, is required for heterochromatin assembly on unpaired chromosomes during C. elegans meiosis. Current Biology, 15, 1972-1978. [PDF]
* Cited by the Faculty of 1000.

Vought V.E., M. Ohmachi, M-H. Lee, and E.M. Maine (2005) EGO-1, a putative RNA-directed RNA polymerase, promotes germline proliferation in parallel with GLP-1/Notch signaling and regulates the spatial organization of nuclear pore complexes and germline P granules in C. elegans. Genetics, 170, 1121-1132. [PDF].

Maine, E.M., D. Hansen, D. Springer, and V.E. Vought (2004) C. elegans atx-2 promotes germline proliferation and the oocyte fate. Genetics 168, 817-830. [PDF].

Smardon, A., J. M. Spoerke, S. C. Stacey, M. E. Klein, N. Mackin, and E. M. Maine (2000) EGO-1 is related to RNA-directed RNA polymerase and functions in germline development and RNA interference in C. elegans. Current Biology 10, 169-178. [PDF].