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.FACULTY PROFILE: Melissa Pepling

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Chen, Y., Jefferson, W., Newbold, R., Padilla-Banks, E. and Pepling, M.E. (2007) Estradiol, Progesterone and Genistein Inhibit Oocyte Nest Breakdown and Primordial Follicle Assembly in the Neonatal Mouse Ovary in vitro and in vivo. Endocrinology 148, 3580-3590.

Greenfeld, C.R., Pepling, M.E., Babus, J.K., Furth, P.A. and Flaws, J.A. (2007) BAX is Involved in Regulating Follicular Endowment in Mice. Reproduction 133, 865-876.

Pepling, M.E., Wilhelm, J.E., O'Hara, A.L., Gephardt, G.W. and Spradling, A.C. (2007) Mouse Oocytes within Germ Cell Cysts and Primordial Follicles Contain a Balbiani Body. PNAS, 104:187-192.

Greenfeld, C.R. , Roby, K., Pepling, M.E., Babus, J.K., Terranova, P.F. and Flaws, J.A. Tumor (2007) Tumor Necrosis Factor Receptor Type 2 is an Important Mediator of TNF alpha Function in the Mouse Ovary.  Biology of Reproduction, 76, 224-237.

Pepling, M.E. (2006) From Primordial Germ Cell to Primordial Follicle: Mammalian Female Germ Cell Development. Genesis 44, 622-632.

Jefferson, W., Newbold, R., Padilla-Banks, E. and Pepling, M.E. (2006) Neonatal genistein treatment alters ovarian differentiation in the mouse: inhibition of oocyte nest breakdown and increased oocyte survival.  Biology of Reproduction. 74:161-168.

Murphy K., Carvajal, L., Medico, L. and Pepling, M. E. (2005) Expression of Stat3 in germ cells of developing and adult mouse ovaries and testes.  Gene Expression Patterns 5, 475-482.

Pepling, M. E. and Spradling, A. C. (2001) The mouse ovary contains germ cell cysts undergo programmed breakdown to form follicles. This article was published in Dev. Biol. 234, 339-351 and is posted with permission from Elsevier. Single copies of the linked article can be downloaded and printed only for the reader's personal reasearch and study. http://www.sciencedirect.com/science/journal/00121606.

Pepling, M. E., de Cuevas, M. and Spradling, A. C. (1999) Germline cysts: A conserved phase of germ cell development. This article was published in Trends Cell Biol. 9, 257-262 and is posted with permission from Elsevier. Single copies of the linked article can be downloaded and printed only for the reader's personal reasearch and study. http://www.sciencedirect.com/science/journal/09628924.

Wolff, C., Pepling, M., Gergen, J. P. and Klingler, M. (1999) Structure and evolution of a pair-rule interaction element: Runt regulatory sequences in D. melanogaster and D. virilis. Mech. Dev. 80, 87-99.

Pepling, M. E. and Spradling, A. C. (1998) Female mouse germ cells form synchronously dividing cysts. Development 125, 3323-332. [PDF]

Tracey, W. D., Pepling, M. E., Horb, M E., Thomsen, G. and Gergen, J. P. (1998) A Xenopus homologue of aml-1 reveals unexpected patterning mechanisms leading to the formation of embryonic blood. Development 125, 1371-1380.

Spradling, A. C., deCuevas, M., Drummond-Barbosa, D., Keyes, L., Lilly, M., Pepling, M. and Xie, T. (1997) The Drosophila germarium: Stem cells, germ line cysts, and oocytes. Cold Spring Harb. Symp. Quant. Biol. 62, 25-34.

Golling, G., Li, L.-H., Pepling, M., Stebbins, M. and Gergen, J. P. (1996) The Brother proteins, Drosophila homologues of the human oncogene, PEBP2/CBFb, regulate the DNA binding and bending properties of Runt. Mol. Cell. Biol. 16, 932-942.

Pepling, M.E. and Gergen, J. P. (1995) Conservation and function of the transcriptional regulatory protein Runt. Proc .Natl. Acad. Sci. 92, 9087-9091.

Kagoshima, H., Shigesada, K., Satake, M., Ito, Y., Miyoshi, H., Ohki, M., Pepling, M. and Gergen, P. (1993) The Runt domain identifies a new family of heteromeric transcriptional regulators. Trends Genet. 9, 338-341.

Kurkulos, M., Weinberg, J. M., Pepling, M. E. and Mount, S. M. (1991) Polyadenylation in copia requires unusually distant upstream sequences. Proc. Natl. Acad. Sci. 88, 3038-3042.

Pepling, M. and Mount, S. M. (1990) Sequence of a cDNA from the Drosophila melanogaster white gene. Nuc. Acids Res. 18, 1633.

 

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